miR-194 suppresses epithelial-mesenchymal transition of retinal pigment epithelial cells by directly targeting ZEB1

BACKGROUND: Epithelial-mesenchymal transition (EMT) of the retinal pigment epithelial (RPE) cells is a critical step in the pathogenesis of proliferative vitreoretinopathy (PVR). Some microRNAs (miRNAs) participate in regulating RPE cell EMT as post-transcriptional regulators. However, the function...

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Vydáno v:Ann Transl Med
Hlavní autoři: Cui, Lian, Lyu, Yali, Jin, Xiaoliang, Wang, Yueye, Li, Xiang, Wang, Juan, Zhang, Jieping, Deng, Zhongzhu, Yang, Nan, Zheng, Zixuan, Guo, Yizheng, Wang, Chao, Mao, Rui, Xu, Jingying, Gao, Furong, Jin, Caixia, Zhang, Jingfa, Tian, Haibin, Xu, Guo-Tong, Lu, Lixia
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2019
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990010/
https://ncbi.nlm.nih.gov/pubmed/32042767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.11.90
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