Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

PURPOSE: Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a key pathological event in proliferative retinal diseases such as proliferative vitreoretinopathy (PVR). This study aimed to explore a new method to reverse EMT in RPE cells to develop an improved therapy...

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Dettagli Bibliografici
Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Chen, Yi, Wu, Binxin, He, Jian Feng, Chen, Jingyao, Kang, Zi Wei, Liu, Dandan, Luo, Junjie, Fang, Kexin, Leng, Xiaoxu, Tian, Haibin, Xu, Jingying, Jin, Caixia, Zhang, Jieping, Wang, Juan, Zhang, Jingfa, Ou, Qingjian, Lu, Lixia, Gao, Furong, Xu, Guo-Tong
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2021
Soggetti:
Retinal Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083104/
https://ncbi.nlm.nih.gov/pubmed/33861322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.4.21
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