Dynamics of Genome Alterations in Crohn’s Disease-Associated Colorectal Carcinogenesis

PURPOSE: Patients with inflammatory bowel diseases, that is, ulcerative colitis and Crohn’s disease (CD), face an increased risk of developing colorectal cancer (CRC). Evidence, mainly from ulcerative colitis, suggests that TP53 mutations represent an initial step in the progression from inflamed co...

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Publicado en:Clin Cancer Res
Autores principales: Hirsch, Daniela, Wangsa, Darawalee, Zhu, Yuelin J., Hu, Yue, Edelman, Daniel C., Meltzer, Paul S., Heselmeyer-Haddad, Kerstin, Ott, Claudia, Kienle, Peter, Galata, Christian, Horisberger, Karoline, Ried, Thomas, Gaiser, Timo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080970/
https://ncbi.nlm.nih.gov/pubmed/29967250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0630
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