Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence

Colorectal adenomas are common precancerous lesions with the potential for malignant transformation to colorectal adenocarcinoma. Endoscopic polypectomy provides an opportunity for cancer prevention; however, recurrence rates are high. We collected formalin-fixed paraffin-embedded tissue of fifteen...

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Veröffentlicht in:Int J Cancer
Hauptverfasser: Fiedler, David, Heselmeyer-Haddad, Kerstin, Hirsch, Daniela, Hernandez, Leanora S., Torres, Irianna, Wangsa, Darawalee, Hu, Yue, Zapata, Luis, Rueschoff, Josef, Belle, Sebastian, Ried, Thomas, Gaiser, Timo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361680/
https://ncbi.nlm.nih.gov/pubmed/30229897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31869
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