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Inferring models of multiscale copy number evolution for single-tumor phylogenetics

Motivation: Phylogenetic algorithms have begun to see widespread use in cancer research to reconstruct processes of evolution in tumor progression. Developing reliable phylogenies for tumor data requires quantitative models of cancer evolution that include the unusual genetic mechanisms by which tum...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Chowdhury, Salim Akhter, Gertz, E. Michael, Wangsa, Darawalee, Heselmeyer-Haddad, Kerstin, Ried, Thomas, Schäffer, Alejandro A., Schwartz, Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481700/
https://ncbi.nlm.nih.gov/pubmed/26072490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv233
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