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Inferring models of multiscale copy number evolution for single-tumor phylogenetics

Motivation: Phylogenetic algorithms have begun to see widespread use in cancer research to reconstruct processes of evolution in tumor progression. Developing reliable phylogenies for tumor data requires quantitative models of cancer evolution that include the unusual genetic mechanisms by which tum...

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Publicat a:Bioinformatics
Autors principals: Chowdhury, Salim Akhter, Gertz, E. Michael, Wangsa, Darawalee, Heselmeyer-Haddad, Kerstin, Ried, Thomas, Schäffer, Alejandro A., Schwartz, Russell
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481700/
https://ncbi.nlm.nih.gov/pubmed/26072490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv233
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