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Algorithms to Model Single Gene, Single Chromosome, and Whole Genome Copy Number Changes Jointly in Tumor Phylogenetics

We present methods to construct phylogenetic models of tumor progression at the cellular level that include copy number changes at the scale of single genes, entire chromosomes, and the whole genome. The methods are designed for data collected by fluorescence in situ hybridization (FISH), an experim...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chowdhury, Salim Akhter, Shackney, Stanley E., Heselmeyer-Haddad, Kerstin, Ried, Thomas, Schäffer, Alejandro A., Schwartz, Russell
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117424/
https://ncbi.nlm.nih.gov/pubmed/25078894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003740
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