Algorithms to Model Single Gene, Single Chromosome, and Whole Genome Copy Number Changes Jointly in Tumor Phylogenetics

We present methods to construct phylogenetic models of tumor progression at the cellular level that include copy number changes at the scale of single genes, entire chromosomes, and the whole genome. The methods are designed for data collected by fluorescence in situ hybridization (FISH), an experim...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chowdhury, Salim Akhter, Shackney, Stanley E., Heselmeyer-Haddad, Kerstin, Ried, Thomas, Schäffer, Alejandro A., Schwartz, Russell
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117424/
https://ncbi.nlm.nih.gov/pubmed/25078894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003740
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki