Dynamics of Genome Alterations in Crohn’s Disease-Associated Colorectal Carcinogenesis

PURPOSE: Patients with inflammatory bowel diseases, that is, ulcerative colitis and Crohn’s disease (CD), face an increased risk of developing colorectal cancer (CRC). Evidence, mainly from ulcerative colitis, suggests that TP53 mutations represent an initial step in the progression from inflamed co...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Hirsch, Daniela, Wangsa, Darawalee, Zhu, Yuelin J., Hu, Yue, Edelman, Daniel C., Meltzer, Paul S., Heselmeyer-Haddad, Kerstin, Ott, Claudia, Kienle, Peter, Galata, Christian, Horisberger, Karoline, Ried, Thomas, Gaiser, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080970/
https://ncbi.nlm.nih.gov/pubmed/29967250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0630
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