Dynamics of Genome Alterations in Crohn’s Disease-Associated Colorectal Carcinogenesis

PURPOSE: Patients with inflammatory bowel diseases, that is, ulcerative colitis and Crohn’s disease (CD), face an increased risk of developing colorectal cancer (CRC). Evidence, mainly from ulcerative colitis, suggests that TP53 mutations represent an initial step in the progression from inflamed co...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Hirsch, Daniela, Wangsa, Darawalee, Zhu, Yuelin J., Hu, Yue, Edelman, Daniel C., Meltzer, Paul S., Heselmeyer-Haddad, Kerstin, Ott, Claudia, Kienle, Peter, Galata, Christian, Horisberger, Karoline, Ried, Thomas, Gaiser, Timo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080970/
https://ncbi.nlm.nih.gov/pubmed/29967250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0630
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