Puerarin Restores Autophagosome-Lysosome Fusion to Alleviate Cadmium-Induced Autophagy Blockade via Restoring the Expression of Rab7 in Hepatocytes

Autophagic dysfunction is one of the main mechanisms by which the environmental pollutant cadmium (Cd) induces cell injury. Puerarin (Pue, a monomeric Chinese herbal medicine extract) has been reported to alleviate Cd-induced cell injury by regulating autophagy pathways; however, its detailed mechan...

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Publicado en:Front Pharmacol
Autores principales: Wang, Tao, Wang, Li, Zhang, Yi, Sun, Jian, Xie, Yilin, Yuan, Yan, Gu, Jianhong, Bian, Jianchun, Liu, Zongping, Zou, Hui
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079953/
https://ncbi.nlm.nih.gov/pubmed/33935722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.632825
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