Puerarin Restores Autophagosome-Lysosome Fusion to Alleviate Cadmium-Induced Autophagy Blockade via Restoring the Expression of Rab7 in Hepatocytes

Autophagic dysfunction is one of the main mechanisms by which the environmental pollutant cadmium (Cd) induces cell injury. Puerarin (Pue, a monomeric Chinese herbal medicine extract) has been reported to alleviate Cd-induced cell injury by regulating autophagy pathways; however, its detailed mechan...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Pharmacol
Κύριοι συγγραφείς: Wang, Tao, Wang, Li, Zhang, Yi, Sun, Jian, Xie, Yilin, Yuan, Yan, Gu, Jianhong, Bian, Jianchun, Liu, Zongping, Zou, Hui
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2021
Θέματα:
Pharmacology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079953/
https://ncbi.nlm.nih.gov/pubmed/33935722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.632825
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