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Puerarin Restores Autophagosome-Lysosome Fusion to Alleviate Cadmium-Induced Autophagy Blockade via Restoring the Expression of Rab7 in Hepatocytes

Autophagic dysfunction is one of the main mechanisms by which the environmental pollutant cadmium (Cd) induces cell injury. Puerarin (Pue, a monomeric Chinese herbal medicine extract) has been reported to alleviate Cd-induced cell injury by regulating autophagy pathways; however, its detailed mechan...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Tao, Wang, Li, Zhang, Yi, Sun, Jian, Xie, Yilin, Yuan, Yan, Gu, Jianhong, Bian, Jianchun, Liu, Zongping, Zou, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079953/
https://ncbi.nlm.nih.gov/pubmed/33935722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.632825
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