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Puerarin Restores Autophagosome-Lysosome Fusion to Alleviate Cadmium-Induced Autophagy Blockade via Restoring the Expression of Rab7 in Hepatocytes

Autophagic dysfunction is one of the main mechanisms by which the environmental pollutant cadmium (Cd) induces cell injury. Puerarin (Pue, a monomeric Chinese herbal medicine extract) has been reported to alleviate Cd-induced cell injury by regulating autophagy pathways; however, its detailed mechan...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Pharmacol
Main Authors: Wang, Tao, Wang, Li, Zhang, Yi, Sun, Jian, Xie, Yilin, Yuan, Yan, Gu, Jianhong, Bian, Jianchun, Liu, Zongping, Zou, Hui
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079953/
https://ncbi.nlm.nih.gov/pubmed/33935722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.632825
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