The ER stress regulator Bip mediates cadmium-induced autophagy and neuronal senescence

Autophagy is protective in cadmium (Cd)-induced oxidative damage. Endoplasmic reticulum (ER) stress has been shown to induce autophagy in a process requiring the unfolded protein response signalling pathways. Cd treatment significantly increased senescence in neuronal cells, which was aggravated by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Wang, Tao, Yuan, Yan, Zou, Hui, Yang, Jinlong, Zhao, Shiwen, Ma, Yonggang, Wang, Yi, Bian, Jianchun, Liu, Xuezhong, Gu, Jianhong, Liu, Zongping, Zhu, Jiaqiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131476/
https://ncbi.nlm.nih.gov/pubmed/27905509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38091
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