Beclin-1-mediated Autophagy Protects Against Cadmium-activated Apoptosis via the Fas/FasL Pathway in Primary Rat Proximal Tubular Cell Culture

The Fas/FasL signaling pathway is one of the primary apoptosis pathways, but the involvement and regulatory mechanism of this pathway by autophagy remain unclear. Here we demonstrated that cadmium (Cd) activated the Fas/FasL apoptosis pathway in rat proximal tubular (rPT) cells; this was accompanied...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Gang, Yuan, Yan, Long, Mengfei, Luo, Tongwang, Bian, Jianchun, Liu, Xuezhong, Gu, Jianhong, Zou, Hui, Song, Ruilong, Wang, Yi, Wang, Lin, Liu, Zongping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430518/
https://ncbi.nlm.nih.gov/pubmed/28428545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00997-w
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