PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway

Parthanatos is a newly discovered form of PARP-1-dependent programmed cell death. It has been reported to play an important role in several cancer or tumour cells; however, few studies have been performed in normal cells. Cadmium is a highly toxic pollutant and is reported to induce autophagy and ap...

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Pubblicato in:Sci Rep
Autori principali: Luo, Tongwang, Yuan, Yan, Yu, Qi, Liu, Gang, Long, Mengfei, Zhang, Kanglei, Bian, Jianchun, Gu, Jianhong, Zou, Hui, Wang, Yi, Zhu, Jiaqiao, Liu, Xuezhong, Liu, Zongping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489486/
https://ncbi.nlm.nih.gov/pubmed/28659599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04555-2
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