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Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture

We designed this study to investigate whether cadmium induces caspase-independent apoptosis and to investigate the relationship between the caspase-dependent and caspase-independent apoptotic pathways. Cadmium (1.25–2.5 μM) induced oxidative stress in rat proximal tubular (rPT) cells, as seen in the...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liu, Gang, Zou, Hui, Luo, Tongwang, Long, Mengfei, Bian, Jianchun, Liu, Xuezhong, Gu, Jianhong, Yuan, Yan, Song, Ruilong, Wang, Yi, Zhu, Jiaqiao, Liu, Zongping
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115828/
https://ncbi.nlm.nih.gov/pubmed/27861627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166823
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