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Salidroside Protects against Cadmium-Induced Hepatotoxicity in Rats via GJIC and MAPK Pathways

It is known that cadmium (Cd) induces cytotoxicity in hepatocytes; however, the underlying mechanism is unclear. Here, we studied the molecular mechanisms of Cd-induced hepatotoxicity in rat liver cells (BRL 3A) and in vivo. We observed that Cd treatment was associated with a time- and concentration...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zou, Hui, Liu, Xuezhong, Han, Tao, Hu, Di, Wang, Yi, Yuan, Yan, Gu, Jianhong, Bian, Jianchun, Zhu, Jiaqiao, Liu, Zong-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466396/
https://ncbi.nlm.nih.gov/pubmed/26070151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129788
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