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Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis

The ciliate Tetrahymena thermophila can either synthesize tetrahymanol or when available, assimilate and modify sterols from its diet. This metabolic shift is mainly driven by transcriptional regulation of genes for tetrahymanol synthesis (TS) and sterol bioconversion (SB). The mechanistic details o...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Hernández, Josefina, Gabrielli, Matías, Costa, Joaquín, Uttaro, Antonio D.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079401/
https://ncbi.nlm.nih.gov/pubmed/33907281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88737-z
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