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Disruption of cholesterol homeostasis by plant sterols

The ABC transporters ABCG5 and ABCG8 limit absorption and promote excretion of dietary plant sterols. It is not known why plant sterols are so assiduously excluded from the body. Here we show that accumulation of plant sterols in mice lacking ABCG5 and ABCG8 (G5G8(–/–) mice) profoundly perturbs chol...

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Bibliografische gegevens
Hoofdauteurs: Yang, Chendong, Yu, Liqing, Li, Weiping, Xu, Fang, Cohen, Jonathan C., Hobbs, Helen H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516266/
https://ncbi.nlm.nih.gov/pubmed/15372105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422186
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