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Disruption of cholesterol homeostasis by plant sterols
The ABC transporters ABCG5 and ABCG8 limit absorption and promote excretion of dietary plant sterols. It is not known why plant sterols are so assiduously excluded from the body. Here we show that accumulation of plant sterols in mice lacking ABCG5 and ABCG8 (G5G8(–/–) mice) profoundly perturbs chol...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516266/ https://ncbi.nlm.nih.gov/pubmed/15372105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422186 |
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