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Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion
Cholesterol and other sterols exit the body primarily by secretion into bile. In patients with sitosterolemia, mutations in either of two ATP-binding cassette (ABC) half-transporters, ABCG5 or ABCG8, lead to reduced secretion of sterols into bile, implicating these transporters in this process. To e...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138595/ https://ncbi.nlm.nih.gov/pubmed/12444248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252582399 |
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