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Relative roles of ABCG5/ABCG8 in liver and intestine
ABCG5 (G5) and ABCG8 (G8) form a sterol transporter that acts in liver and intestine to prevent accumulation of dietary sterols. Mutations in either G5 or G8 cause sitosterolemia, a recessive disorder characterized by sterol accumulation and premature coronary atherosclerosis. Hepatic G5G8 mediates...
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| Pubblicato in: | J Lipid Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306686/ https://ncbi.nlm.nih.gov/pubmed/25378657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054544 |
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