Relative roles of ABCG5/ABCG8 in liver and intestine

ABCG5 (G5) and ABCG8 (G8) form a sterol transporter that acts in liver and intestine to prevent accumulation of dietary sterols. Mutations in either G5 or G8 cause sitosterolemia, a recessive disorder characterized by sterol accumulation and premature coronary atherosclerosis. Hepatic G5G8 mediates...

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Bibliografiske detaljer
Udgivet i:J Lipid Res
Main Authors: Wang, Jin, Mitsche, Matthew A., Lütjohann, Dieter, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2015
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306686/
https://ncbi.nlm.nih.gov/pubmed/25378657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054544
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