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The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice

The main player in biliary cholesterol secretion is the heterodimeric transporter complex, ABCG5/ABCG8, the function of which is necessary for the majority of sterols secreted into bile. It is not clear whether the primary step in this process is flopping of cholesterol from the inner to the outer l...

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Détails bibliographiques
Auteurs principaux: Kosters, Astrid, Kunne, Cindy, Looije, Norbert, Patel, Shailendra B., Oude Elferink, Ronald P. J., Groen, Albert K.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805467/
https://ncbi.nlm.nih.gov/pubmed/16741293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M500511-JLR200
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