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Quantifying Anomalous Intestinal Sterol Uptake, Lymphatic Transport, and Biliary Secretion in Abcg8(-/-) Mice

Sitosterolemia is caused by mutations in either ABCG5 or ABCG8, but simultaneous mutations of these genes have never been observed. To explore whether ABCG8, the sterol efflux (hemi-) transporter, plays a major role in determining intestinal absorption efficiency and hepatic secretion rates of chole...

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Detalhes bibliográficos
Main Authors: Wang, Helen H., Patel, Shailendra B., Carey, Martin C., Wang, David Q.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906848/
https://ncbi.nlm.nih.gov/pubmed/17393508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21579
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