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Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

Cholesterol and other sterols exit the body primarily by secretion into bile. In patients with sitosterolemia, mutations in either of two ATP-binding cassette (ABC) half-transporters, ABCG5 or ABCG8, lead to reduced secretion of sterols into bile, implicating these transporters in this process. To e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yu, Liqing, Hammer, Robert E., Li-Hawkins, Jia, von Bergmann, Klaus, Lutjohann, Dieter, Cohen, Jonathan C., Hobbs, Helen H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2002
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC138595/
https://ncbi.nlm.nih.gov/pubmed/12444248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252582399
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