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Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis

The ciliate Tetrahymena thermophila can either synthesize tetrahymanol or when available, assimilate and modify sterols from its diet. This metabolic shift is mainly driven by transcriptional regulation of genes for tetrahymanol synthesis (TS) and sterol bioconversion (SB). The mechanistic details o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hernández, Josefina, Gabrielli, Matías, Costa, Joaquín, Uttaro, Antonio D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079401/
https://ncbi.nlm.nih.gov/pubmed/33907281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88737-z
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