Insulin-like Growth Factors are Key Regulators of T helper 17-Regulatory T Cell Balance in Autoimmunity

Appropriate balance of T helper-17 (Th17) and regulatory T (Treg) cells maintains immune tolerance and host defense. Disruption of Th17-Treg cell balance is implicated in a number of immune-mediated diseases, many of which display dysregulation of the insulin-like growth factor (IGF) system. Here, w...

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Publicado no:Immunity
Main Authors: DiToro, Daniel, Harbour, Stacey N., Bando, Jennifer K., Benevides, Gloria, Witte, Steven, Laufer, Vincent A., Moseley, Carson, Singer, Jeffery R., Frey, Blake, Turner, Henrietta, Bruning, Jens, Darley-Usmar, Victor, Gao, Min, Conover, Cheryl, Hatton, Robin D., Frank, Stuart, Colonna, Marco, Weaver, Casey T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078727/
https://ncbi.nlm.nih.gov/pubmed/32294406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.03.013
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