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Late Developmental Plasticity in the T Helper 17 Lineage

Development of T helper (Th) 17 cells requires transforming growth factor (TGF)-β and interleukin (IL)-6 and is independent of the Th1 pathway. Although T cells that produce interferon (IFN)-γ are a recognized feature of Th17 cell responses, mice deficient for STAT4 and T-bet—two prototypical Th1 tr...

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Detalhes bibliográficos
Main Authors: Lee, Yun Kyung, Turner, Henrietta, Maynard, Craig L., Oliver, James R., Chen, Dongquan, Elson, Charles O., Weaver, Casey T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607320/
https://ncbi.nlm.nih.gov/pubmed/19119024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.11.005
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