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Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals
Two models are proposed to explain Notch function during helper T (Th) cell differentiation. One argues that Notch instructs one Th cell fate over the other, whereas the other posits that Notch function is dictated by cytokines. Here we provide a detailed mechanistic study investigating the role of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762693/ https://ncbi.nlm.nih.gov/pubmed/23890069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.07.006 |
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