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Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals

Two models are proposed to explain Notch function during helper T (Th) cell differentiation. One argues that Notch instructs one Th cell fate over the other, whereas the other posits that Notch function is dictated by cytokines. Here we provide a detailed mechanistic study investigating the role of...

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Detaylı Bibliyografya
Asıl Yazarlar: Bailis, Will, Yashiro-Ohtani, Yumi, Fang, Terry C., Hatton, Robin D., Weaver, Casey T., Artis, David, Pear, Warren S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762693/
https://ncbi.nlm.nih.gov/pubmed/23890069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.07.006
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