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Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
Precise control of the timing and magnitude of Notch signaling is essential for the normal development of many tissues, but the feedback loops that regulate Notch are poorly understood. Developing T cells provide an excellent context to address this issue. Notch1 signals initiate T-cell development...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714710/ https://ncbi.nlm.nih.gov/pubmed/19605688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1793709 |
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