Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy

The enzyme glutamine synthetase (GS), also referred to as glutamate ammonia ligase, is abundant in astrocytes and catalyzes the conversion of ammonia and glutamate to glutamine. Deficiency or dysfunction of astrocytic GS in discrete brain regions have been associated with several types of epilepsy,...

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Bibliografiske detaljer
Udgivet i:Front Neurol
Main Authors: Sandhu, Mani Ratnesh S., Gruenbaum, Benjamin F., Gruenbaum, Shaun E., Dhaher, Roni, Deshpande, Ketaki, Funaro, Melissa C., Lee, Tih-Shih W., Zaveri, Hitten P., Eid, Tore
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Neurology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078591/
https://ncbi.nlm.nih.gov/pubmed/33927688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.665334
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