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Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy

The enzyme glutamine synthetase (GS), also referred to as glutamate ammonia ligase, is abundant in astrocytes and catalyzes the conversion of ammonia and glutamate to glutamine. Deficiency or dysfunction of astrocytic GS in discrete brain regions have been associated with several types of epilepsy,...

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Dades bibliogràfiques
Publicat a:Front Neurol
Autors principals: Sandhu, Mani Ratnesh S., Gruenbaum, Benjamin F., Gruenbaum, Shaun E., Dhaher, Roni, Deshpande, Ketaki, Funaro, Melissa C., Lee, Tih-Shih W., Zaveri, Hitten P., Eid, Tore
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078591/
https://ncbi.nlm.nih.gov/pubmed/33927688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.665334
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