Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort

BACKGROUND: There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the release of mitochondrial DNA (mtDNA), but plasma cell-free mtDNA has not been previ...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Zhang, William Z., Hoffman, Katherine L., Schiffer, Kristen T., Oromendia, Clara, Rice, Michelle C., Barjaktarevic, Igor, Peters, Stephen P., Putcha, Nirupama, Bowler, Russell P., Wells, J. Michael, Couper, David J., Labaki, Wassim W., Curtis, Jeffrey L., Han, Meilan K., Paine, Robert, Woodruff, Prescott G., Criner, Gerard J., Hansel, Nadia N., Diaz, Ivan, Ballman, Karla V., Nakahira, Kiichi, Choi, Mary E., Martinez, Fernando J., Choi, Augustine M. K., Cloonan, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074408/
https://ncbi.nlm.nih.gov/pubmed/33902556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01707-x
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