Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort

BACKGROUND: There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the release of mitochondrial DNA (mtDNA), but plasma cell-free mtDNA has not been previ...

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Bibliografski detalji
Izdano u:Respir Res
Glavni autori: Zhang, William Z., Hoffman, Katherine L., Schiffer, Kristen T., Oromendia, Clara, Rice, Michelle C., Barjaktarevic, Igor, Peters, Stephen P., Putcha, Nirupama, Bowler, Russell P., Wells, J. Michael, Couper, David J., Labaki, Wassim W., Curtis, Jeffrey L., Han, Meilan K., Paine, Robert, Woodruff, Prescott G., Criner, Gerard J., Hansel, Nadia N., Diaz, Ivan, Ballman, Karla V., Nakahira, Kiichi, Choi, Mary E., Martinez, Fernando J., Choi, Augustine M. K., Cloonan, Suzanne M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074408/
https://ncbi.nlm.nih.gov/pubmed/33902556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01707-x
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