Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of age-related dementia. Increasing evidence suggests that neuroinflammation mediated by microglia and astrocytes contributes to disease progression and severity in AD and other neurodegenerative disorders. During AD progression, resident microglia u...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Park, Jong-Sung, Kam, Tae-In, Lee, Saebom, Park, Hyejin, Oh, Yumin, Kwon, Seung-Hwan, Song, Jae-Jin, Kim, Donghoon, Kim, Hyunhee, Jhaldiyal, Aanishaa, Na, Dong Hee, Lee, Kang Choon, Park, Eun Ji, Pomper, Martin G., Pletnikova, Olga, Troncoso, Juan C., Ko, Han Seok, Dawson, Valina L., Dawson, Ted M., Lee, Seulki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074239/
https://ncbi.nlm.nih.gov/pubmed/33902708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01180-z
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