Lysosomal Enzyme Glucocerebrosidase Protects against Aβ(1-42) Oligomer-Induced Neurotoxicity

Glucocerebrosidase (GCase) functions as a lysosomal enzyme and its mutations are known to be related to many neurodegenerative diseases, including Gaucher’s disease (GD), Parkinson’s disease (PD), and Dementia with Lewy Bodies (DLB). However, there is little information about the role of GCase in th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choi, Seulah, Kim, Donghoon, Kam, Tae-In, Yun, Seungpil, Kim, Sangjune, Park, Hyejin, Hwang, Heehong, Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668030/
https://ncbi.nlm.nih.gov/pubmed/26629917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143854
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados