Lysosomal Enzyme Glucocerebrosidase Protects against Aβ(1-42) Oligomer-Induced Neurotoxicity

Glucocerebrosidase (GCase) functions as a lysosomal enzyme and its mutations are known to be related to many neurodegenerative diseases, including Gaucher’s disease (GD), Parkinson’s disease (PD), and Dementia with Lewy Bodies (DLB). However, there is little information about the role of GCase in th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Choi, Seulah, Kim, Donghoon, Kam, Tae-In, Yun, Seungpil, Kim, Sangjune, Park, Hyejin, Hwang, Heehong, Pletnikova, Olga, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668030/
https://ncbi.nlm.nih.gov/pubmed/26629917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143854
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