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Glucocerebrosidase: Functions in and Beyond the Lysosome
Glucocerebrosidase (GCase) is a retaining β-glucosidase with acid pH optimum metabolizing the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose. Inherited deficiency of GCase causes the lysosomal storage disorder named Gaucher disease (GD). In GCase-deficient GD patients the accumu...
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| Publicado no: | J Clin Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7141376/ https://ncbi.nlm.nih.gov/pubmed/32182893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9030736 |
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