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In situ visualization of glucocerebrosidase in human skin tissue: zymography versus activity-based probe labeling
Epidermal β-glucocerebrosidase (GBA1), an acid β-glucosidase normally located in lysosomes, converts (glucosyl)ceramides into ceramides, which is crucial to generate an optimal barrier function of the outermost skin layer, the stratum corneum (SC). Here we report on two developed in situ methods to...
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| Vydáno v: | J Lipid Res |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Biochemistry and Molecular Biology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711493/ https://ncbi.nlm.nih.gov/pubmed/29025868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079376 |
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