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The A1 astrocyte paradigm: New avenues for pharmacologic intervention in neurodegeneration
We recently demonstrated that NLY01, a novel glucagon-like peptide receptor 1 (GLP1R) agonist, exerts neuroprotective effects in two mouse models of Parkinson disease (PD) in a glia-dependent manner. NLY01 prevented microglia from releasing inflammatory mediators known to convert astrocytes into a n...
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| Publicado no: | Mov Disord |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642014/ https://ncbi.nlm.nih.gov/pubmed/31136698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27718 |
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