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HIC1 Represses Atoh1 Transcription and Hair Cell Differentiation in the Cochlea

Across species, expression of the basic helix-loop-helix transcription factor ATOH1 promotes differentiation of cochlear supporting cells to sensory hair cells required for hearing. In mammals, this process is limited to development, whereas nonmammalian vertebrates can also regenerate hair cells af...

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Dades bibliogràfiques
Publicat a:Stem Cell Reports
Autors principals: Abdul-Aziz, Dunia, Hathiramani, Nicolai, Phung, Lauren, Sykopetrites, Vittoria, Edge, Albert S.B.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072069/
https://ncbi.nlm.nih.gov/pubmed/33770497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.02.022
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