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HIC1 Represses Atoh1 Transcription and Hair Cell Differentiation in the Cochlea

Across species, expression of the basic helix-loop-helix transcription factor ATOH1 promotes differentiation of cochlear supporting cells to sensory hair cells required for hearing. In mammals, this process is limited to development, whereas nonmammalian vertebrates can also regenerate hair cells af...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Abdul-Aziz, Dunia, Hathiramani, Nicolai, Phung, Lauren, Sykopetrites, Vittoria, Edge, Albert S.B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072069/
https://ncbi.nlm.nih.gov/pubmed/33770497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.02.022
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