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ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea

In mammals, cochlear hair cells are not regenerated once they are lost, leading to permanent hearing deficits. In other vertebrates, the adjacent supporting cells act as a stem cell compartment, in that they both proliferate and differentiate into de novo auditory hair cells. Although there is evide...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Neurosci
Hauptverfasser: Zhang, Jingyuan, Wang, Quan, Abdul-Aziz, Dunia, Mattiacio, Jonelle, Edge, Albert S.B., White, Patricia M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234075/
https://ncbi.nlm.nih.gov/pubmed/30270571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14183
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