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ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea

In mammals, cochlear hair cells are not regenerated once they are lost, leading to permanent hearing deficits. In other vertebrates, the adjacent supporting cells act as a stem cell compartment, in that they both proliferate and differentiate into de novo auditory hair cells. Although there is evide...

詳細記述

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書誌詳細
出版年:Eur J Neurosci
主要な著者: Zhang, Jingyuan, Wang, Quan, Abdul-Aziz, Dunia, Mattiacio, Jonelle, Edge, Albert S.B., White, Patricia M.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6234075/
https://ncbi.nlm.nih.gov/pubmed/30270571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14183
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