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Epigenetic regulation of Atoh1 guides hair cell development in the mammalian cochlea
In the developing cochlea, sensory hair cell differentiation depends on the regulated expression of the bHLH transcription factor Atoh1. In mammals, if hair cells die they do not regenerate, leading to permanent deafness. By contrast, in non-mammalian vertebrates robust regeneration occurs through u...
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631768/ https://ncbi.nlm.nih.gov/pubmed/26487780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126763 |
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