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Selection of cell fate in the organ of Corti involves the integration of Hes/Hey signaling at the Atoh1 promoter

Determination of cell fate within the prosensory domain of the developing cochlear duct relies on the temporal and spatial regulation of the bHLH transcription factor Atoh1. Auditory hair cells and supporting cells arise in a wave of differentiation that patterns them into discrete rows mediated by...

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Détails bibliographiques
Publié dans:Development
Auteurs principaux: Abdolazimi, Yassan, Stojanova, Zlatka, Segil, Neil
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813338/
https://ncbi.nlm.nih.gov/pubmed/26932672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.129320
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