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HIC1 Represses Atoh1 Transcription and Hair Cell Differentiation in the Cochlea

Across species, expression of the basic helix-loop-helix transcription factor ATOH1 promotes differentiation of cochlear supporting cells to sensory hair cells required for hearing. In mammals, this process is limited to development, whereas nonmammalian vertebrates can also regenerate hair cells af...

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Detalles Bibliográficos
Publicado en:Stem Cell Reports
Autores principales: Abdul-Aziz, Dunia, Hathiramani, Nicolai, Phung, Lauren, Sykopetrites, Vittoria, Edge, Albert S.B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072069/
https://ncbi.nlm.nih.gov/pubmed/33770497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.02.022
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