Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance of hematopoietic stem cells is not clear. We generated an Aplnr-tdTo...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Jackson, Melany, Fidanza, Antonella, Taylor, A. Helen, Rybtsov, Stanislav, Axton, Richard, Kydonaki, Maria, Meek, Stephen, Burdon, Tom, Medvinsky, Alexander, Forrester, Lesley M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072025/
https://ncbi.nlm.nih.gov/pubmed/33667414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.02.003
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