Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System

Apelin receptor (APLNR/AGTRLl1/APJ) marks a transient cell population during the differentiation of hematopoietic stem and progenitor cells (HSPCs) from pluripotent stem cells, but its function during the production and maintenance of hematopoietic stem cells is not clear. We generated an Aplnr-tdTo...

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Publicat a:Stem Cell Reports
Autors principals: Jackson, Melany, Fidanza, Antonella, Taylor, A. Helen, Rybtsov, Stanislav, Axton, Richard, Kydonaki, Maria, Meek, Stephen, Burdon, Tom, Medvinsky, Alexander, Forrester, Lesley M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072025/
https://ncbi.nlm.nih.gov/pubmed/33667414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.02.003
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