Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs

Hematopoietic stem and progenitor cells (HSPCs) develop in distinct waves at various anatomical sites during embryonic development. The in vitro differentiation of human pluripotent stem cells (hPSCs) recapitulates some of these processes; however, it has proven difficult to generate functional hema...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Fidanza, Antonella, Stumpf, Patrick S., Ramachandran, Prakash, Tamagno, Sara, Babtie, Ann, Lopez-Yrigoyen, Martha, Taylor, A. Helen, Easterbrook, Jennifer, Henderson, Beth E. P., Axton, Richard, Henderson, Neil C., Medvinsky, Alexander, Ottersbach, Katrin, Romanò, Nicola, Forrester, Lesley M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862875/
https://ncbi.nlm.nih.gov/pubmed/32614947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006229
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