Simultaneous Expression of Th1- and Treg-Associated Chemokine Genes and CD4(+), CD8(+), and Foxp3(+) Cells in the Premalignant Lesions of 4NQO-Induced Mouse Tongue Tumorigenesis

SIMPLE SUMMARY: Oral squamous cell carcinoma (OSCC), the most common oral malignancy, severely impacts patient quality of life because of oro-facial destruction. OSCC is preceded by oral premalignant lesions (OPLs). Moreover, lower T cell infiltration in OPLs is associated with OSCC, suggesting that...

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Yamaguchi, Hana, Hiroi, Miki, Mori, Kazumasa, Ushio, Ryosuke, Matsumoto, Ari, Yamamoto, Nobuharu, Shimada, Jun, Ohmori, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069711/
https://ncbi.nlm.nih.gov/pubmed/33921389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081835
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